Nature Reviews Genetics

natrevgenet.nature.com

09 November 2025 17:54

New online! Decoding the regulatory genome with large-scale deep learning

Sina Majidian

sinamajidian.bsky.social

07 November 2025 15:09

Yijie Kang (CSHL, Stony Brook) from @pkoo562.bsky.social Lab presented "Decoding the sequence basis of Pol II elongation with deep learning"

Anshul Kundaje

anshulkundaje.bsky.social

28 June 2025 20:42

One thing that really bothers me with the new "virtual cell" terminology is that it is currently largely focused on a very narrow definition of models that can predict effects of trans perturbations (gene dosage, drugs etc) on gene expression. 1/

Anshul Kundaje

anshulkundaje.bsky.social

25 June 2025 17:41

This a really exciting leap forward for genomic sequence to activity gene regulation models. It is a genuine improvement over pretty much all SOTA models spanning a wide range of regulatory, transcriptional and post-transcriptional processes. 1/

Žiga Avsec

avsecz.bsky.social

25 June 2025 17:40

Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind