Liedewij Laan
liedewijlaan.bsky.social
Scientist, mother of 3, art lover, physics of life, (bottom-up) synthetic biology, evolution, philosophy of science, TU Delft, www.tudelft.nl/laanlab, founder BiBB https://www.betainbestuurenbeleid.nl/nl/about-us
👤 Joined on 18 October 2023
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- 18 Eki 2023, 19:16
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@liedewijlaan.bsky.social - 10 Kas 2023, 04:16
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ooh Bluesky can do videos now... here's an emergency #cilia movie
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New preprint from the lab: The Latent Simplicity of Microbial Ecological Interactions www.biorxiv.org/content/10.6... We're excited about this one. We find that high-order microbial interactions often obey simple linear laws, making microbial communities far more predictable than one might expect.
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www.biorxiv.org/content/10.6...
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In this way the biophysical requirement for bulk electrostatic interaction may widen the allowable sequence space for Ndc80C, facilitating its evolution. We think this is a powerful way to understand how the kinetochore is able to vary so substantially while conserving function 10/12
Show PostMoving forward, I want to see how sequence variation in Ndc80C may impact higher order properties like oligomerization (cf PMID: 41880487), which could diversify kinetochore mechanics across eukaryotes. Here, Naegleria’s especially divergent Ndc80C and microtubules may be illuminating 11/12
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