I've complained on here a few times about synteny plots that are harder to read than they need to be. I decided it was time to actaully do something about it: introducing SynTangle, a tool for untangling whole-genome synteny plots github.com/Hanliconius/... 1/

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@joethorntonlab.bsky.social and I are thrilled to co-organize the 2027 Molecular Mechanisms in Evolution GRC, June 13–18, in beautiful Portland, Maine! See our ⭐stellar⭐ lineup of speakers ⬇️ spanning evolutionary biochemistry, cell biology, development, behavior... www.grc.org/molecular-me... 1/n

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We are looking for a postdoc. Candidates should have a PhD, at least one first-author paper, hands-on cryo-EM experience, and strong protein biochemistry skills. Please send your CV, research statement, and contact information for three references.

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Excited to share Shotgun Genetic Engineering, developed by @julietrolle.bsky.social out now @natbiotech.nature.com! Read on to learn how Julie enabled mammalian cells to grow without 2 essential amino acids for the first time in >500 million years using highly multiplexed metabolic engineering!

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🚨🚨Preprint alert!🚨🚨 We removed the main centromere 3 domain of Drosophila‼️ We designed an inducible dCas9-Fok1 system to cut 🧬 at unique sequences flanking the ~50-kb island where most of CENP-A sits. To our knowledge, this has never been attempted in a living animal!

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