Stephan Hacker

stephanhacker2.bsky.social

16 September 2026 14:04

How can we figure out, how protein activity is controlled in space and time? I am very happy that @janavolaric.bsky.social joined the @led3hub.bsky.social as an NWO VENI fellow this year to address exactly this question using exciting optical tools. (1/3) #ChemSky #ChemBio #Light #LipidTime #Lipids

Stephan Hacker

stephanhacker2.bsky.social

16 September 2026 14:04

Do you need to replace a functional group in your molecule with a #bioisostere? @drughunter.com just released an interesting free resource in their "Bioisosteres Cheat Sheet". drughunter.com/resource/bio... #ChemSky #ChemBio #DrugDiscovery #Science

Schwalbe Lab

schwalbe-lab.bsky.social

15 July 2026 02:08

Thanks for having us as collaborators on this! @olallalab.bsky.social Congrats to everyone involved in developing a platform for photoswitchable RNA binders, enabling light-controlled RNA modulation and RNA-targeted therapeutics. Full text: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Sophia Paul

sophia-pa.bsky.social

08 July 2026 15:48

Thank you, @schullerjm.bsky.social for the great support and many thanks to all the collaborators and colleagues that made this project possible. Thankful for your insights and support: @tomaspascoa.bsky.social @stripplab.bsky.social @olallalab.bsky.social

Sophia Paul

sophia-pa.bsky.social

08 July 2026 15:47

Excited to share my paper! 🥳 Today in #Nature we reveal an 8 MDa Hdr electron bifurcating super-assembly in class I methanogens that couples the first and last steps of hydrogenotrophic methanogenesis. A lineage-specific adaptation to anaerobic niches. www.nature.com/articles/s41...