New paper by Harshath Amal @harshath.bsky.social shows how TGF-β signaling controls epithelial permeability by regulating actomyosin contractility and adhesion. Surprisingly, elevated adhesion can maintain barrier integrity independently of contractility tinyurl.com/ywenrexy @jcellsci.bsky.social

Show Post

🎉 Our paper is out today in @science.org! How does the intestine maintain the right balance of cell types? We find that signalling rhythms matter! So proud of our three shared first authors, Sonja Weterings, @hiromuneeto.bsky.social & @jddeleede.bsky.social! 🔗 www.science.org/doi/10.1126/...

Show Post

Bloop 🫧 bloop 🫧 bloop 🫧 Fluid-filled lumens are everywhere in our body How do they get soooo big? We find that osmotic pressure vastly dominates mechanical forces in controlling lumen swelling in mouse embryos biorxiv.org/content/10.6... @louise-dagher.bsky.social @matteo-bassanini.bsky.social

Show Post

Even wonder how the leopard got its spots? I certainly did, so much that I tried to recreate similar patterns in a dish! Hear about the results from my postdoctoral work in this #spotLight. Many thanks to @reinierprosee.bsky.social for putting this together. And yes, even the soundtrack is homemade!

Show Post

Check out my latest thread for @epimechfc.bsky.social and dive into how a 70 yr old mathematical theory may explain pattern self-organisation in biology!

Show Post