Osama Harraz

osamaharraz.bsky.social

16 October 2026 02:29

🧠Hypertension changes how brain blood vessels sense mechanical forces. Overactive Piezo1 disrupts cerebral blood flow and cognition, while Piezo1 inhibition reverses these deficits in mice. Congratulations to the team and collaborators! ahajournals.org/doi/10.1161/... @ahascience.bsky.social

Osama Harraz

osamaharraz.bsky.social

09 August 2026 12:45

Check out our latest article! Tau and ion channels (Piezo1 and Kir2.1) in brain capillaries.

Jorge Castorena

jcastorena.bsky.social

04 June 2026 23:23

A lot remains to be uncovered about the underlying signaling in lymphatic GLP-1Rs, but this is the first of hopefully many studies on this newish project from our lab. Congrats to @maryschulz.bsky.social on her second first author publication with our lab during her PhD.

Jorge Castorena

jcastorena.bsky.social

04 June 2026 23:23

Our newest study is now published. Here we show that GLP-1Rs are expressed in the lymphatic vasculature and enriched in LECs. And pharmacological activation by semaglutide enhances the pumping capacity of collectors. onlinelibrary.wiley.com/doi/10.1111/...

Ardem Patapoutian

ardemp.bskyverified.social

05 March 2026 10:18

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function. www.nature.com/articles/s41...