🐟 New preprint ! 🐟 For Hippo pathway aficionados. We generated a CRISPR/Cas9 mediated single-copy endogenous Yap1-mGreenLantern fusion protein in medaka to follow Yap1 dynamics in vivo, through embryogenesis and beyond. And it is such a beautiful line ! 🧵

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Our article is on the COVER of this month’s issue of @cp-devcell.bsky.social! Congrats to all the authors for the hard work, especially Shota, Despina and @jamesbriscoe.bsky.social

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Our work on the role of the proteasome in developmental tempo is out!!!! 🐭⌛️👤⏳ Six years after identifying an association between protein stability and developmental tempo, we now demonstrate a causal link between protein turnover and developmental tempo through proteasomal degradation

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A recent EMBL study published in Developmental Cell could help explain why humans develop slower than mice. The teams analysed 4,000 genes and found that protein degradation in humans tends to be significantly slower than in mice. www.embl.org/news/science...

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First published teamwork of the lab 🎉! We wrote a review about emerging concepts of how metabolism promotes, regulates and changes during gastrulation. We hope it will be useful for anyone interested in the emerging field of developmental metabolism. www.sciencedirect.com/science/arti...

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