Peter
biotechpedro.bsky.social
PhD student at Fraticelli lab @irbbarcelona.org I try to convert coffee into code and ideas to uncover biological mysteries. I enjoy creativity more than productivity. Single-cell, lineage tracing, computational biology, cellular variability, [...]
👤 Joined on 30 October 2024
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- 30 Eki 2024, 10:21
🎉 Bluesky'e katıldı - İlk kullanıcı adı:
@biotechpedro.bsky.social
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1/7 ❄️ Very happy to share our new study: “Cold activates a BH2 metabolic network promoting longevity and proteostasis.” nature.com/articles/s41... #Aging #Longevity #Proteostasis #Metabolism #ALS #HuntingtonsDisease
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Love 🦤radEmu🦤? You'll love ☄️fastEmu☄️! Fantastic work by @steichman.bsky.social fastEmu replaces a computationally expensive piece of hypothesis testing in radEmu with a cheaper approximation. Especially beneficial for large datasets & complex designs! Software: statdivlab.github.io/fastEmu Enjoy!
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We've thought about including CellSweep! According to their lovely tutorial (cellsweep.readthedocs.io/en/latest/tu...) they actually already recommend removing doublets before using CellSweep so we figured they're aware of the potential impacts their tool has on doublet detection.
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Order Matters: Ambient RNA correction confounds doublet detection in single-cell RNA sequencing https://www.biorxiv.org/content/10.64898/2026.10.13.758369v1
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If you’re working with Flex data, be careful when doing ambient RNA correction! It turns out that removing ambient RNA (in particular with decontX), and *then* doing doublet ID, can seriously reduce doublet detection performance ‼️
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