Carl A Michal (Physics & Astronomy, The University of British Columbia, Canada) A low-cost spectrometer for NMR measurements in the Earth's magnetic field, Measurement Science and Technology, 2010, Volume 21, Number 10, 105902 iopscience.iop.org/article/10.1... #NMRchat 🧲

Show Post

Enzymes are powerful tools for chemical synthesis, but their natural setting within a microbe’s metabolism can limit their industrial use. Cell-free biosynthesis aims to sidestep that constraint by using isolated enzymes instead of intact microbes. #chemsky 🧪

Show Post

🚨New preprint! Ligands at the same GPCR can produce wildly different signaling outputs. Why? We built a mutational scanning platform to measure ~10,000 µOR variants across 15 opioids, yielding ~400k measurements of how sequence and ligand chemistry set signaling. www.biorxiv.org/content/10.6... 1/10

Show Post

🚀Excited to share our new paper #NatureCommunications 🎉! We uncover a 🧨 #CrypticPocket in #CRISPR #Cas9 that forms transiently on super short timescales not trapped by #cryoEM! 🧬This pocket enables metal ions to regulate #DNA cleavage! 🔗 hhttps://www.nature.com/articles/s41467-026-78458-0

Show Post

In 1971, the landmark meeting “Structure and Function of Proteins at the Three Dimensional Level.” was held at Cold Spring Harbor Laboratory. It provided a venue for ongoing conversations about what it would mean for all scientists to have access to the structural data 1/4

Show Post