Karolin Luger

nucleosomepolice.bsky.social

15 August 2025 17:07

Thinking about a career change....

Karolin Luger

nucleosomepolice.bsky.social

06 August 2025 20:05

Still in a nice place..

ahellab.bsky.social

10 July 2025 20:09

A few years back we discovered a dual hybrid protein modification composed of ADP-ribose dinucleotide and ubiquitin (ADPr-Ub). Now we reveal that ADPr-Ub can be further ubiquitinated by the E3 ubiquitin ligase RNF114! www.nature.com/articles/s41... www.science.org/doi/10.1126/...

ahellab.bsky.social

12 June 2025 13:36

Our new paper is out! Trying to understand the molecular function of the PARP7, a PARP family enzyme with links to innate immunity and environmental toxins response. Congrats to Andrii and the rest of the team and collaborators. www.pnas.org/doi/10.1073/...

Anthony Leung

leunglab.bsky.social

08 April 2025 19:54

🥳 Out now @embojournal.org! Interferon induces a new class of p62 bodies, with #antiviral & #immunotherapy implications. p62 is usually linked to #autophagy — but not here. These are driven by PARP14-mediated ADP-ribosylation & rely on #ubiquitin #proteasome system. www.embopress.org/doi/full/10....