loldeloo.bsky.social
Associate professor of Psychiatry, Human Genetics, and Computational Medicine at UCLA
👤 Joined on 19 November 2024
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@loldeloo.bsky.socialClever study using founder effect to identify novel genes associated with transdiagnostic serious mental illness #BioMed
Show PostI had an early view of this as part of Greta Gerdes external thesis proposal advisory (don’t believe she is on here…), but no other involvement, it’s one of the most exciting findings on psychiatric genetics, due to both the genetics ANd The phenotyping. www.medrxiv.org/content/10.6...
Show Postkallisto sped up RNA-seq quantification by 50x. Now another 50x speedup... quantify hundreds of millions of reads in a few seconds. This seems too good to be true. But it's true! Incredible accomplishment by @pmelsted.bsky.social.
Show PostHere is the "effective payline" for each institute, estimated (by Claude) as the percentile where one can expect 80% probability of funding from a logistic regression fit. The effective payline has gone from a historic ~12% to 6% in 2025.
Show Post🧬New today! 📄Inclusion bias affects common variant discovery and replication in a health-system linked biobank 🧑🤝🧑 @loldeloo.bsky.social @apimplaskar.bsky.social @bpasaniuc.bsky.social & colleagues
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