prismscienceorg.bsky.social
Prism is building the full stack of technologies and algorithms necessary to make protein motion measurable, actionable, and predictable. Learn more at prismscience.org
👤 Joined on 11 August 2025
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@diffuseproject.bsky.social@diffuseproject.bsky.social → @prismscience.bsky.social@prismscience.bsky.social → @prismscienceorg.bsky.socialEmergency 🚨 TTPD with @fraserlab.com about the launch of @prismscienceorg.bsky.social. podcasts.apple.com/us/podcast/p...
Show PostProteins are always moving. They wiggle. They jiggle. They interact with their surroundings. That movement drives their function. Yet the motion stays mostly invisible. We cannot understand protein function, engineer it, or correct it until we can see the motion and predict it. prismscience.org
Show PostWaterFlow: Prediction of Ordered Water Molecule Positions on Protein Structures https://www.biorxiv.org/content/10.64898/2026.08.26.747373v1
Show PostCode: github.com/diff-use/WaterFlow
Show PostWe can show the same against reciprocal space data. Predicted water molecules 4RKW with no refinement at all and R-free is 0.227 against the deposited model's 0.200. Light refinement closes the gap to 0.012.
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