dlwagnerlabs.bsky.social
International research group (Berlin & Houston) led by @dlwagner.bsky.social CAR-T cells | Non-viral genome engineering | CRISPR | Precision editing | Large knock-ins | Integrases |
👤 Joined on 17 September 2025
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@dlwagnerlabs.bsky.social“Good things take time” Allogeneic Treg do not prevent their own rejection in immunocompetent hosts - HLA matching or HLA editing required for optional function! A beautiful collaboration with Fadi Issa & Joanna Hester’s team @ox.ac.uk. @dlwagnerlabs.bsky.social
Show PostHLA matching or CRISPR editing HLA-I/II enables engraftment & function of allo human Treg therapy in a humanized mouse transplantation model @natcomms.nature.com @dlwagner.bsky.social @bcmhouston.bsky.social www.nature.com/articles/s41...
Show PostClass is in session! 🚀 Star Trek: Starfleet Academy premieres Jan 15, 2026 on Paramount+. Get ready cadets. #StarTrek #StarfleetAcademy #ParamountPlus #tvsky
Show Post@dlwagnerlabs.bsky.social on tour! 🌍🇩🇪🇺🇸 We had a great time at the Annual Congress of the European Society for Gene and Cell Therapy #ESGCT2025 in Sevilla. 🇪🇸 Super proud of everyone who presented their projects & grateful for working with this amazing team: science and good vibes! 🧬🧪💙
Show PostCheck out one of our latest stories about combining our non viral knock-in strategy with integrases for an efficient, targeted integration of transgenes >8kb in human T cells! ‘One-pot’ PASTA: programmable and site specific transgene addition - all in just one reaction 🫕
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