Another chapter in Ju Chen lab’s FLNC saga, this time toward gene therapy. Three AAVs + split inteins overcome the cargo limit to restore full-length filamin C and prevent FLNC-deficient cardiomyopathy in mice. doi.org/10.1172/JCI2...

Show Post

What Three Gene-Therapy Deaths Have in Common - The virus used to deliver healing DNA in gene therapy is under renewed scrutiny. | The Atlantic www.theatlantic.com/health/2026/...

Show Post

Congrats @bohlen.bsky.social!

Show Post

Congratulations to Dr. Martin Bohlen @bohlen.bsky.social, Research Scientist in Duke BME, for receiving the Cajal Club's Editor's Choice Award! He shares the honor with co-authors A. Horn, S. Warren, & P. May for two 2025 papers (titles/links below). @cajalclub.bsky.social @springernature.com

Show Post

Correct! We've got a fairly generic method for turning optogenetic tools into magnetogenetic tools. It's a decent amount of work to make them good, but the zero-to-one hit rate is surprisingly high.

Show Post