connorjtou.bsky.social
PhD from MIT BE, Kleinstiver lab || Editing genes and running mountains
👤 Joined on 12 November 2024
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@connorjtou.bsky.socialGene-editing techniques could soon allow researchers to replace entire genes and engineer complex cellular circuits — if the systems can be delivered safely into cells go.nature.com/4z4UP5W
Show Post🎉 Our first paper from the Querques lab is out! We uncover the molecular checkpoints controlling cut-and-paste transposition by CRISPR-associated transposons. Congrats to Mateusz & the whole team! 🧬 www.nature.com/articles/s41... @univie.ac.at @meduniwien.ac.at
Show PostINSTALLing recombinase-driven genome writing: Engineered single-stranded donors bypass innate immunity to enable large DNA integration
Show PostRead the research highlight from Frank Buchholz in Molecular Cell on INSTALL - a recombinase-driven approach using engineered single-stranded donors that bypass innate immunity. www.sciencedirect.com/science/arti... #Science #Biotech #GeneTherapy #Innovation
Show PostA belated re-post after a brief sci-media hiatus - congratulations to @connorjtou.bsky.social & the team! We sought to overcome a key challenge for inserting large DNAs into the genome: toxicity & innate immune responses. 🧬 🚫 Our paper was published in @nature.com: www.nature.com/articles/s41...
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