jinfanwang.bsky.social
Assistant Professor @ UTSW biochemistry/ Ribosome/Single-molecule biophysics/mitochondria
👤 Joined on 27 January 2025
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- 27 Oca 2025, 14:10
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Our new smFRET assay to follow intersubunit rotation of eukaryotic ribosomes during translation elongation is out: academic.oup.com/nar/article/...
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STOP using ipTM for #AlphaFold PPI screens. * Artificially LOW when both full-length proteins have irrelevant, non-binding IDRs/domains. * If one protein is folded & other contains irrelevant IDRs or domains, the score is too HIGH bc of d0. * Use ipSAE or LIS. www.biorxiv.org/content/10.1...
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It is a great privilege to be named Mencoff Family RNA Research Professor of Molecular Biology, Cell Biology and Biochemistry at Brown University. I am grateful to Mencoff Family, Brown University, Department of Molecular Biology, Cell Biology, and Biochemistry and Guiliani RNA Center.
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New preprint from Kaley Simcox in the Koutmou lab! She developed a HILIC-MS/MS approach for total tRNA sequencing, achieving 75–100% coverage for most isoacceptors - without ion-pairing reagents. This enabled the discovery of new modified positions on E. coli tRNAs. doi.org/10.64898/202...
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