Snippert lab

Snippert lab

hugosnippert.bsky.social

We use human organoid models to study the emergence and transformation of early-stage colorectal cancer. We aim to prevent rather than cure. Research lab at Prinses Maxima Center (formerly at UMC Utrecht) & Oncode Institute https://snippertlab.nl

👤 Joined on 22 November 2024

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  • 22 Kas 2024, 16:20
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @hugosnippert.bsky.social

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Congratulations to @landau.bsky.social, New York Genome Center Core Faculty Member, a 2026 Recipient of a Lotus Award from the Pershing Square Foundation www.nygenome.org/news-events/...

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Short write-up of our journey. Searching for T cell transcription factors, Marc v/d Wetering stumbled across Wnt signaling. Vladja Korinek linked Wnt to colon cancer and crypt biology. Nick Barker discovered the gut stem cell. Toshi Sato invented organoids authors.elsevier.com/a/1n3No6tu0C...

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OrganoidNL was an excellent meeting with a range of exciting topics. A bonus was visiting Micropia, a unique museum in Amsterdam dedicated to microbes, where even living tardigrades and slime molds are on display

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Very proud to share our new paper on early cancer progression, published in Nature! Beyond the science itself, this project really shows what strong interdisciplinary collaboration can achieve. I feel grateful to have been part of this amazing team. Check out our discoveries below!

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Excited to share our latest work in Nature. Applying single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune B cells, suggesting that somatic mutations may be key to autoimmunity [1/n] rdcu.be/fdqbr

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