🧩 B cell depletion is highly effective in multiple sclerosis. But why? In our new @brain1878.bsky.social paper, we used ocrelizumab as a perturbation, uncovering a B cell-dependent T cell state linking peripheral immune activation to chronic CNS inflammation. doi.org/10.1093/brain/awag303 🧵👇 1/

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We’re excited to be heading to Bristol this Thursday and Friday for our annual College Tutors’ meeting! A big thank you to dbRotas for being our premium sponsor this year. 🔗 https://ow.ly/n11650Z9sPz

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Excited to be at the #QEIICentre today! As co-founders of @dbrotas.bsky.social and alumni of Cohort 7 of the #NHS Clinical Entrepreneur Programme, we're delighted to be sharing how algorithm-driven personalised rota creation is helping transform workforce planning across 20+ NHS Trusts!

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The current HD-ISS doesn't incorporate wet biomarkers. Dr. Mena Farag discusses the promising results of proenkephalin and other biomarkers to help monitor the earliest stages of HD before the onset of motor symptoms. https://loom.ly/j3VrGFs

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Discovery of disrupted sustained attention and altered functional connectivity in far‐from‐onset Huntington's disease gene‐expanded young adults alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

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