dbgoodman.bsky.social
Assistant Professor at UPenn. Synthetic immunologist & computational biologist. Using DNA synth, multiplex assays and generative models to understand & engineer immune cell signaling & function. Church lab alum. Web: www.dbgoodman.com
👤 Joined on 10 September 2023
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@dbgoodman.bsky.socialAAV opens up the 80% of genome considered 'undruggable'. A key challenge and opportunity is to search that space for the right targets. Manufacturing capacity is sufficient to serve tens of millions of patients at safe doses, as long as we can find the right targets for efficacy.
Show PostI miss when the biggest controversy about mRNA was whether it correlated with protein or not.
Show PostAn SRO I have worked with on and off for 10+ yrs was fired. This person had almost 20 years of experience in their job and had cultivated an entire discipline by managing fair, through and rigorous reviews of grants across the entire field. How heartbreaking.
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