Our collaborative paper on #Nanopore sequencing is now available on #BioRxiv. Among several new variants, we characterize a large duplication in the IGHC region, suggesting non-canonical class switching between the duplicated isotypes in #Bcells. www.biorxiv.org/content/10.1...

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Did you know that human immunoglobulin constant genes are crazy diverse? It's got me thinking...Proud of Uddalok Jana! And grateful for collabs @guryaari.bsky.social @williamlees.bsky.social @ayeletperes.bsky.social @e-engelbrecht1.bsky.social @yscientist.bsky.social www.biorxiv.org/content/10.1...

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Check out long-read sequencing results in human IGH! HUGE duplications in constant gene regions...and 7 copies of IGHV3-23 on one haplotype! @lossiusandreas.bsky.social @williamlees.bsky.social www.biorxiv.org/content/10.1...

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So Kristi Noem goes on Fox and lies that Sen Padilla didn’t ID himself, even though the video is there for all to see. But get what she’s saying: Assaulting and handcuffing someone for trying to ask a question is OK in any case? This is a criminal regime.

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Anyone that has been around a lab knows that the trainees really drive the research, while most professors just sort of guide the ship. Most innovation comes from our trainees. Old professors like me will be able to survive these cuts, but our young scientists and our future will be destroyed.

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