Sorek Lab

soreklab.bsky.social

17 October 2026 21:52

Very nice discovery from the Jackson, Bravo and Basel labs. Cleaved tRNA ends, loaded with an amino acid, activate a form of bacterial immunity

Panos Spatharas

pspatharas.bsky.social

15 October 2026 08:26

1/1 How does a single methyl group activate bacterial defence? In my PhD work with @matthiaswilmanns.bsky.social and @typaslab.bsky.social, we reveal how this tiny DNA modification triggers retron disassembly and toxin activation. Now on bioRxiv: www.biorxiv.org/content/10.6...

Structura Biotechnology

structurabio.bsky.social

14 October 2026 12:26

Connecting image formation to data processing provides valuable context for interpreting your data, identifying potential artifacts, and understanding the principles behind downstream processing. All this and more, in the #CryoSPARC Guide 👉 guide.cryosparc.com/cryo-em-foun...

Typas Lab

typaslab.bsky.social

14 October 2026 08:45

How does a single methyl group activate bacterial defence? Our new preprint, led by @pspatharas.bsky.social in collaboration with the group of @matthiaswilmanns.bsky.social, explains how a single DNA methylation event activates large retron assemblies. www.biorxiv.org/content/10.6...

John Rubinstein

johnrubinstein.bsky.social

09 October 2026 12:53

29(!) years ago I visited Richard Henderson at LMB to ask about doing a PhD. Richard asked Sarah, a senior student, to take me for a (truly terrible, this was England in the 90s) coffee at Addenbrooks hospital to talk about grad student life at LMB. Amazing what Sarah has accomplished since then!