dviousmind.bsky.social
Genomics technologist, SynBio enthusiast and AI hacker at the WEHI Advanced Genomics Facility. Views and opinions are my own.
👤 Joined on 24 November 2024
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@dviousmind.bsky.socialFinal message: if you are engineering proteins for therapeutic use, remember to take into account #production, #aggregation and #bioactivity. These factors count when it comes to making a drug! As Ntombizodwa Makuyana demonstrated in vivo, with 3-fold better production from #AAV. 10/11
Show PostKey Takeaways: • No AF2 retraining needed • Works with X-ray & cryo-EM/cryo-ET • If you formulate a likelihood target, you can test with your favorite data type • Refines large-scale conformational changes • Robust at low resolution • Enables automated experiment-guided refinement 10/14
Show PostCommercial guy avoiding to give the $/Gb price.
Show PostCongratulations @jabyrnesci.bsky.social on winning the well-deserved David Vaux Research Integrity Fellowship Award. bit.ly/4aVDilW
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