cmcclune.bsky.social
Plants, specialized metabolism, synthetic biology, protein evolution, and everything in between. Postdoc at Sattley & Fordyce Labs, Stanford Previously SynBio @ Voigt & Laub Labs, MIT
👤 Joined on 09 November 2024
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@c-mcclune.bsky.social@c-mcclune.bsky.social → @cmcclune.bsky.socialExcited to share the first published paper from my lab! Postdoc Helen Jordan led this study on 1) how metabolites change differently in inflammation in tissues versus in cells in a dish and 2) the role of one of the most-increased metabolites, soluble sialic acid www.jbc.org/article/S002...
Show PostComplete elucidation and heterologous reconstruction of the biosynthetic pathway of camptothecin #PlantScience #SecMet From: www.biorxiv.org/content/10.6...
Show PostTargeted DNA insertion remains a major bottleneck in plant engineering. We developed an avian R2 retrotransposon as an efficient plant genome editor to precisely insert large DNA payloads at targeted sites: www.nature.com/articles/s41... Congratulations to @kimuchenje03.bsky.social and the team! 🧵👇
Show Post🌿🧬 Taxol pathway mapped with new method mpXsn. Seventeen genes known, eight newly discovered. Baccatin III produced in tobacco at natural levels. Breakthrough for anti-cancer drug production. #plantscience @cmcclune.bsky.social @sattelylab.bsky.social @nature.com www.nature.com/articles/s41...
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