busrasavas.bsky.social
PhD student IBG & DEU | Computational Structural Biologist
👤 Joined on 13 January 2024
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@busrasavas.bsky.social🔔Our latest special issue, guest edited by Dr. Panagiotis L. Kastritis, is now live! 🧊 Eight reviews explore the role of cryo-EM in understanding diverse complexes, painting a picture of a field moving toward greater understanding of metabolic architecture. ❄️ tinyurl.com/FEBSCryoEM
Show PostOnly a couple of days left to introduce our brand new tool, DynaPIN that @aysebercinb.bsky.social developed (in collaboration with @sacquin-mo.bsky.social & co.) to analyze dynamic/ensemble protein interfaces!
Show PostSo I thought I'd make a quick semi-replacement (a python script using gemmi & mkdssp, mostly written with Codex). It just takes the PDB/mmcif & plots the sequence, with secondary structure from mkdssp, and colors the secondary structure by pLDDT or B-factor. (2/3)
Show PostAlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions 📄 research.nvidia.com/labs/dbr/ass... 🌐 alphafold.ebi.ac.uk
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