lauraamike.bsky.social
Mike Lab @ Pitt-ID www.themikelab.com Studying how Kleb regulates capsule properties and causes infection #klebclub | #newPI
👤 Joined on 23 August 2023
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@lauraamike.bsky.socialKlebsiella pneumoniae is one of the most common causes of UTI, yet how it actually causes disease is still poorly defined. These clinical isolates varied widely in capsule, mucoidy, and serum resistance. Even so, all established pyelonephritis. I’m curious what conserved factor drives that ascent.
Show PostNice story, Laura! Good to see people looking beyond #UPEC for bacterial virulence and microenvironmental influences like this. #UTISky #MicroSky
Show PostOur new paper shows AstR is required to activate ornithine catabolism for A. baumannii to compete with the microbiota in the gut reservoir Led by fantastic first authors John Geary and Xiaomei Ren! 🥳
Show Post#Bacteria Ornithine utilization is important for Acinetobacter baumannii during gut colonization. A protein that regulates ornithine catabolism helps the pathogen to sense and respond to competition for amino acids with the resident microbiota @xiaomeiren.bsky.social @laurenpalmer.bsky.social
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