melikel.bsky.social
Professor, Physiology Department, Perelman School of Medicine, University of Pennsylvania. https://www.lakadamyali-lab.com Super resolution microscopy, single molecule biophysics, microtubules, organelles, nucleus and chromatin
👤 Joined on 28 November 2023
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@melikel.bsky.social1/ Our paper, “Enhancer binding kinetics explain transcription factor hub formation,” is now published! Here we set out to understand why transcription factors form bright clusters or “hubs” in the nucleus, and whether those hubs actually control gene activity. tinyurl.com/38uf8348
Show Post🚨Our work #ReScale4DL: balancing pixel and contextual information for enhanced bioimage segmentation, with @henriqueslab.bsky.social is out today!🚀 www.nature.com/articles/s41... ReScale4DL links key concepts in DL (receptive fields)+microscopy (resolution) so they can work #bettertogether😉 Threat👇
Show PostDid you not invite the girls…? And why did you only start doing that after I left…??
Show Post1/ out in @science.org! We found a new asymmetry in large-scale chromosome structure: sister chromatids are shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! A close collaboration w/ @gerlichlab.bsky.social , led by @flaviacorsi.bsky.social www.science.org/doi/10.1126/...
Show PostNew paper from the lab! We developed a self-organizing bovine muscle and blood vessel-like network from ES cells, bringing us one step closer to creating structured cultured beef steak! 🥩🔬 www.nature.com/articles/s41... 1/
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