kevinkelley.bsky.social
Assistant Professor Stanford. Neuroscientist and psychiatrist. Cellular and molecular mechanisms of human brain development and disease.
👤 Joined on 18 November 2024
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@kevinkelley.bsky.social1/6 An extraordinary @nature.com paper has just landed from the lab of @sergiuppasca.bsky.social. They found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells.
Show PostJust out in Nature an extraordinary paper by @sergiuppasca.bsky.social and his team who genetically altered mice & transferred organoids derived from human neural cells into the cortex. @anilseth.bsky.social and I explore the ethical implications in a forthcoming commentary.
Show PostReplacing the mouse cortex with human-derived brain organoids could offer a new way to study how circuits form and conditions such as autism. By @briannaabbott.bsky.social www.thetransmitter.org/spectrum/hum...
Show PostThe experimental strategy overcomes hurdles that have long stymied researchers studying neuropsychiatric illness in lab-grown brain tissue go.nature.com/4ixYQe1
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