santoslab.bsky.social
Quantitative stem cell biologist and group leader @TheCrick Institute. Cell decision-making. Cell fate and cell division. @Stanford, @EMBL alumna. ENTP. Mum. Diver.
👤 Joined on 14 May 2025
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@santoslab.bsky.socialDeparting from Susumu Ohno’s classic hypothesis, I will propose that X-chromosome inactivation arose not to correct excess X-linked gene dosage in females, but to give XX cells an advantage in coping with dominant deleterious mutations.
Show PostI will propose a revised hypothesis for the evolution of dosage compensation in mammals: compensation on autosomes first, followed by X-chromosome upregulation as the Y chromosome evolved.
Show PostRecruiting! Joint PhD studentship with the laboratory of Silvia Santos @santoslab.bsky.social at the Francis Crick institute to examine the mechanics and growth control of human post-gastrulation amnioids. Deadline: 03/11/2026. Details on the project: www.crick.ac.uk/careers-stud...
Show PostWebsite for EMBO workshop on cell cycle and development is active. Amazing lineup of speakers. Please spread the word. @matildegalli.bsky.social, @santoslab.bsky.social and I are happy to answer questions. Looking forward to seeing many of you in Amsterdam in June meetings.embo.org/event/27-cel...
Show PostWhy optogenetics deserves the hype www.wiringthebrain.com/2013/09/why-... (a piece I wrote in 2013 explaining how it works and why modulating specific cell types is so key to understanding how neural circuits and systems work)
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