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Amy D Willis

@amydwillis.bsky.social did:plc:vdrpi3cx2tacjdfugmvav3ez

Biodiversity-loving, error bar-needing statistics nerd; Associate Professor @UWBiostat. Methods & software for #microbiome & #biodiversity data. She/her.

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Amy D Willis (@amydwillis.bsky.social), 2 Ekim 2023 tarihinde katılan bir Bluesky kullanıcısı. 630 takipçisi var, 134 hesabı takip ediyor ve 101 post paylaştı.

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  • Dutchscientist 🚴👨‍🎓 & Meg the Tuxie 😺@dutchscientist.bsky.social

    My pleasure. Trees based on sequence alignments will show the effects of differences in sequence, but need interpretation to use that for evolutionary conclusions. Bootstrapping analysis just says something about the tree construction process, and how reliable the branching is. A bit like p-values!

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  • Dutchscientist 🚴👨‍🎓 & Meg the Tuxie 😺@dutchscientist.bsky.social

    And like p-values, bootstrapping values are expected, whether useful or not 😉

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  • Steven Robbins@stevenjrobbins.bsky.social

    It's out! Excited to present the Great Barrier Reef Microbial Genomes Database (GBR-MGD), a comprehensive DB of 1000s of high-quality prokaryote, virus, plasmid, and chromosome-level eukaryote MAGs using Nanopore long reads. Subthreads incoming. Please share widely. 🙂 www.nature.com/articles/s41...

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  • Erik van Nimwegen@erikvannimwegen.bsky.social

    that the bootstrap values or posteriors are of much interest for such data in any case. In the BEST case scenario they reflect uncertainty due only to the data being a finite sample under the assumption that ALL assumptions the model makes are true.

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  • Dutchscientist 🚴👨‍🎓 & Meg the Tuxie 😺@dutchscientist.bsky.social

    It depends very much how they did the bootstrapping. If done with MEGA, not much, as that is a "cheating" way of fast bootstrapping. Did they do bootstrapping (replacement) or jackknifing (deletion)? But it say mostly something about the alignments, treeing algorithm and topology, not evolution.

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