Leiden Early Drug Discovery & Development (LED3)
@led3hub.bsky.social did:plc:jnlt3o3km3ebst2vcigkwdch
LED3 is a hub of scientists working on early drug discovery at the Leiden Institute of Chemistry, the Leiden Academic Centre for Drug Research, the Institute of Biology Leiden and the Leiden Institute of Advanced Computer Science. @[email protected]
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Leiden Early Drug Discovery & Development (LED3) (@led3hub.bsky.social) é um usuário do Bluesky desde 19 setembro 2023. Tem 819 seguidores, segue 42 contas e publicou 231 posts.
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I had an amazing time visiting @yale.edu and presenting some of the work of our group. A huge thank you to @jeanjuchung.bsky.social and Felix Zhu for inviting me and to everyone for the interesting discussions (@craigmcrews.bsky.social, Hongying Shen, Jing Hughes, Yansheng Liu, David Zenisek).
Ver postAnother great LED3 Lecture.
Ver postAmazing @led3hub.bsky.social Lecture by Marc Robillard from Tagworks Pharmaceuticals. He talked about the development of Click-to-Release chemistry and its application to antibody-drug conjugates that can be activated by a chemical trigger. www.nature.com/articles/s42...
Ver post#DrugDiscovery #Click #ClickChemistry #ClickToRelease #ADC #ChemBio #ChemSky #Chemistry
Ver post🔹 Structural Validation: In collaboration with Tessa Gote and @armstrongchembio.bsky.social within our @led3hub.bsky.social, we resolved a crystal structure of the protein in complex with our top hit. This revealed covalent engagement at C111 and key interactions for future optimization. (5/8)
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