Xilin Jiang

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• Nikhil Milind@nikhilmilind.dev29-10-2026 23:37

  How well does TWAS estimate a gene’s direction of effect on a trait? We think of this as an important stress-test for the accuracy of TWAS. In a new paper, we find that TWAS gets the sign wrong around 20-30% of the time! www.nature.com/articles/s41...

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• Jonathan Pritchard@jkpritch.bsky.social29-10-2026 23:37

  Latest work from our lab: we find that current TWAS pipelines often fail to recover correct directions of effects. This is an important caveat for many downstream applications such as trait causal modeling. Great work by Peter Gerlach and @nikhilmilind.dev

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• Jonathan Pritchard@jkpritch.bsky.social10-10-2026 16:06

  I want to try something again at #ASHG26: I'll block off some time on Weds/Th/Friday afternoons to meet with trainees who would be interested to chat on any topic. I have done this the last 2 years and it was great to meet a whole bunch of new people, from many countries, at all career stages!

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• Faculté de biologie et de médecine@fbm-unil.bsky.social10-10-2026 16:06

  Publication alert 🚨 on #genetic #epidemiology to help improve interpretability and more accurately characterize how genetic effects on complex traits change over the #lifespan By @tabeasch.bsky.social et al. and led by @zkutalik.bsky.social In @nataging.nature.com 🔗 www.nature.com/articles/s43...

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• Arun Durvasula@arundurvasula.bsky.social25-09-2026 09:36

  *that I am an author on. I realize in retrospect that you can quote any @biorxivpreprint.bsky.social post and say “new manuscript!”

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