Nathaniel Blalock
@nathanielblalock.bsky.social did:plc:ocsgl3gb6addmzsacrcaf2v3
Graduate Research Assistant in Dr. Philip Romero's Lab at Duke/Wisconsin Reinforcement and Deep Learning for Protein Redesign | He/him
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Nathaniel Blalock (@nathanielblalock.bsky.social) es un usuario de Bluesky que se unió el 17 diciembre 2024. Tiene 138 seguidores, sigue a 425 cuentas y ha publicado 20 posts.
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We present an end-to-end differentiable Bayesian framework for learning the latent parameters of coarse-grained potentials for IDPs. By optimizing a likelihood objective via importance-weighted gradients, we align generative protein ensembles with experimental observables doi.org/10.1529/biop...
Ver postLooking for an awesome PhD in Germany at the interface of AI, small molecule design, and health? Go work with the awesome Andrea Volkamer on AI-driven discovery of safer new organic materials that avoid human toxicity! Volkamer group: volkamerlab.org position: www.uni-saarland.de/fileadmin/up...
Ver postCan we learn protein biology from a language model? In new work led by @liambai.bsky.social and me, we explore how sparse autoencoders can help us understand biology—going from mechanistic interpretability to mechanistic biology.
Ver post"Adapting ProteinMPNN for antibody design without retraining" Our several-years-old fix to ProteinMPNN's tendency to make weird antibody CDR sequences is finally preprinted
Ver postTwo more🙃: 1) arxiv.org/abs/2412.12979 2) arxiv.org/abs/2505.15093
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