Giacomo Bignardi
@giacomobignardi.bsky.social did:plc:kicquzfsoqvcgpbdwcei2uql
Postdoctoral researcher at the Max Planck Institute for Empirical Aesthetics, Behavior Genetics Unit Typos are my owl
En Bluesky desde el
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Resumen
Giacomo Bignardi (@giacomobignardi.bsky.social) es un usuario de Bluesky que se unió el 14 septiembre 2023. Tiene 593 seguidores, sigue a 376 cuentas y ha publicado 145 posts.
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"Never try to convey your idea to the audience - it is a thankless and senseless task. Show them life, and they’ll find within themselves the means to assess and appreciate it." — Andrei Tarkovsky, Russian director
Ver postVery proud to share the bulk work from my postdoc, now out in @Nature!! Introducing phase 1 of the TenK10K dataset, with matched WGS and single-cell RNA-seq from almost 2,000 individuals www.nature.com/articles/s41... 🧬🧵👇 (1/n)
Ver postStudy of 367 bird species (74k elements, 5.9k songs) including vocal learners (oscines. hummingbirds) & nonlearners (suboscines, nightjars) + 52 human languages (15k elements, 800 speech/song phrases) suggests convergent motor mechanisms in bird & human vocalizations, independent of vocal learning.🧪
Ver post1/n Out today in @Nature: our Alzheimer’s disease GWAS of ~2.8M people (~184k cases). We find 48 new loci, ~3x higher SNP-heritability, enrichment in genes up-regulated in microglia and down-regulated in neurons, and we release public summary statistics. www.nature.com/articles/s41...
Ver post“AD is the most common cause of dementia. Analysing 109k cases, 74k proxy cases, 2M controls & 500k proxy controls, we identified 118 loci in multi-ancestry + 9 in ancestry-specific analyses. We show that common-variant contributions have been substantially underestimated, & reveal new mechanisms.”🧪
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