Dr. Seema Mattoo
@mattoolab.bsky.social did:plc:ioatetiez5eaavxhr5e5chlq
Assoc. Professor, Purdue U. (via India - U. Maryland, College Park - UCLA - UCSD/HHMI). Having fun studying Fic proteins, from bacteria to humans. #AMPylation #HypothesisFund https://www.bio.purdue.edu/lab/mattoo/
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Dr. Seema Mattoo (@mattoolab.bsky.social) ist seit 25 November 2023 auf Bluesky. Das Konto hat 766 Follower, folgt 136 Konten und hat 85 Posts veröffentlicht.
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🧵🦠New paper out in mSystems! We mapped the pan-genome #T6SS effector arsenal of #Pantoea agglomerans. The surprise: its weapons live in dynamic genomic armories that mix antibacterial attack with anti-phage defense. 1/n journals.asm.org/doi/10.1128/...
Post anzeigenMost grateful to Nature Immunology for highlighting our recent discovery of receptor-free TLR signal transduction @natimmunol.nature.com www.nature.com/articles/s41...
Post anzeigenExcited to share a new preprint from my, @brodskyigorlab.bsky.social, & Ted Kreider's labs led by amazing postdocs Ling Wu & Kimmie Wodzanowski, & student Stephanie Schreiner! We show that human CASP4 & 5 form inflammasomes in response to distinct LPS structures. 1/n www.biorxiv.org/content/10.6...
Post anzeigenAnother view of the inner plasma membrane of a glioblastoma cell, imaged by platinum replica electron microscopy. This image, ~1.2 µm wide, shows curved clathrin honeycombs, fingerprint-patterned caveolae, and actin cytoskeleton attachments. Image by graduate student Lila Gordon in the lab.
Post anzeigenJust in time for Halloween, we've posted a new preprint on zombie deubiquitinases! As it turns out, standard #DUB catalytic mutants aren't truly dead - they've just become zombies that are still capable of removing noncanonical, ester-linked #ubiquitin signals...
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