Florian Naudet
@floriannaudet.bsky.social did:plc:3nuyftkga5q32inooxbbxa74
Meta-researcher, Clinician, Professor at Rennes University, Senior member at Institut Universitaire de France, affiliate at METRICStanford. ORCID: 0000-0003-3760-3801 Posts are my own. Website: https://restores.univ-rennes.fr/
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Florian Naudet (@floriannaudet.bsky.social) ist seit 27 August 2023 auf Bluesky. Das Konto hat 2.650 Follower, folgt 3.529 Konten und hat 1.081 Posts veröffentlicht.
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By early Nov the @ec.europa.eu will roll out an expanded version of its Open Research Europe (ORE) platform using the ‘publish, review, curate’ model launched by eLife in 2022 www.nature.com/artic... Holly Else Mario Malički Nature
Post anzeigenNew @jamanetworkopen.com article entitled "Clinical Evidence on Psilocybin and Its Representation in Media Reporting: A Systematic Review" Of possible interest to @floriannaudet.bsky.social @garyschw.bsky.social @eikofried.bsky.social @ioanaacristea.bsky.social jamanetwork.com/journals/jam...
Post anzeigen1/ UK's Medicines and Healthcare products Regulatory Agency just updated safety measures for antidepressant use. Regarding suicide risk, they rely on a recent systematic review of RCTs. And here is where the problems start. Thread (started today, may get longer over time)
Post anzeigen2/ The review in question by Li et al. looked for all published (!) RCTs which reported results of suicide ideation 2, 8, and 12 weeks. www.sciencedirect.com/science/arti... This resulted an a very small selection of existing antidepressant trials: 7 to 16 trials only!
Post anzeigen3/ Just compare this to the data available to the FDA (Stone et al. 2009, BMJ), with 295 trials and about 27,000 participants! Therefore, the review by Li et al. is a tiny fraction of all available trials. And it gets worse
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