We’re recruiting postdocs! Join our Emerging Fields consortium to explore ribosome biology and translational control in pediatric cancers. My lab combines high-resolution Ribo-seq with unbiased genetic screens to uncover novel regulatory mechanisms. Deadline: 15 Nov 2026 lnkd.in/dmKJ7zbb

Show Post

Our new review in Current Opinion in Structural Biology is out! We discuss how multicolour #SingleMolecule imaging reveals gene expression in action - from #Transcription and #RNA processing to #Translation, molecular coupling, and live-cell tracking. doi.org/10.1016/j.sb... #smFRET @embl.org

Show Post

Chaperone isoform and interactome mapping reveals functional diversification of DNAJA2-DNAJA4 complexes via stress-regulated isoforms www.biorxiv.org/content/10.6...

Show Post

🧬 Happy to see our paper finally out! Here we show that a post-translational modification tunes Hsp70–J-domain protein interaction by unfolding of the J-domain. This either blocks Hsp70 engagement or leads to protein degradation. Check out how this phospho-switch rewires chaperone networks:

Show Post

A conserved tyrosine motif encodes a structural vulnerability controlling stability and activity across J-domain proteins This interesting story, which involved several labs and some ideas of my own, has finally been released. www.nature.com/articles/s42...

Show Post