Frank Harrell

Frank Harrell

f2harrell.bsky.social

Professor of Biostatistics Vanderbilt University School of Medicine Consultant, clinical trials/drug development https://hbiostat.org https://fharrell.com

👤 Joined on 12 October 2023

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  • 12 Eki 2023, 12:29
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @f2harrell.bsky.social
  • 09 Kas 2023, 04:05
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❤️ Beğendiği Gönderiler

Kert Viele
14 October 2026 11:31

I'm also unfamiliar, but it's an interesting question. In addition to within-patient variation, I'd worry about biases. Patients may self select out of the OLE, or there are restrictions like meeting inclusion criteria again (patients meeting it twice might not look like patients meeting it once)

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Q trial statistics: Any literature on analyzing open-label extension RCTs as individual stepped wedge trials, taking into account the within-patient information? @kertviele.bsky.social @stephensenn.bsky.social @f2harrell.bsky.social @statsepi.bsky.social @jdwilko.bsky.social Please tag others!

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Ben Bolker
12 October 2026 21:23

fun photo of 5 MB of data on punch cards (from www.lanl.gov/media/public... , via this article on programmer Mary Tsingou en.wikipedia.org/wiki/Mary_Ts... : www.nytimes.com/2026/10/10/s... )

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I was traveling and conferencing last week, so naturally the amount of email and DMs I have this Monday morning is truly impossible to conquer. Please be patient as I spend the next few days digging

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I am way too online for my own good, and I had an unreasonably large twitter following, and I really *enjoyed* twitter for a lot of years, and yet leaving there and never looking back was maybe the easiest what-felt-like-a-big-ethical decision I've ever made.

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