A fun thread/paper for my bio-nerd friends. (Craig, Brandon, Gabi: I see you.)

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A decade after beginning the project, Ryan McGee, Olivia Kosterlitz, Artem Kaznatcheev, Ben Kerr, and I have a paper in PNAS this week that is one of the best pieces of work I've ever been involved in. Without paywall: carlbergstrom.com/publications... Below, a thread about (part of) the paper.

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This thread is already tl;dr, so I'll wrap things up here. A thorough discussion of the theory will have to wait for another thread or, in the meantime, it's all here in the paper. If you made it this far, thank you!

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A cell must be infected by significantly more than one viral genome simultaneously for the virus to overcome the cell's innate immune defenses and successfully replicate @cp-cell.bsky.social www.cell.com/cell/fulltex...

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Using #worldanvil to keep all my details straight. There’s lots too remember in this world.

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