Signal Transduction and Targeted Therapy

sigtrans-sttt.bsky.social

31 Oktober 2026 22:30

Cells rely on protein quality control to maintain their health and function. This review explores how ER-associated degradation and #ERphagy preserve cellular balance and contribute to disease, highlighting their therapeutic potential. #STTT #OpenAccess: doi.org/10.1038/s413...

Harvard Med Cell Biology

harvardcellbio.bsky.social

30 Oktober 2026 21:18

Work from the @harperlabhms.bsky.social & Johannes Walter labs reveals a structural interactome resource for the Golgi apparatus that combines crosslinking organelle proteomics with structural predictions across the Golgi proteome.@asapresearch.parkinsonsroadmap.org www.biorxiv.org/content/10.6...

Iva Tolić

ivatolic.bsky.social

30 Oktober 2026 15:39

How does the mitotic spindle adapt to genomes that differ in size by more than 10,000-fold? Our paper in @natcellbio.nature.com reveals a simple scaling law and the physics behind it: chromosome crowding! 🧵 www.nature.com/articles/s41...

Journal of Cell Biology

jcb.org

30 Oktober 2026 15:38

Adhesion integrity activates mechanosensitive proliferative signaling. New study from Lídia Faria, Florence Janody and colleagues @i3suporto.bsky.social: rupress.org/jcb/article/... #CellSignaling #Biophysics #Cancer #Cytoskeleton #Mechanobiology #Cadherin

Alex Merz 🇺🇸🇨🇦🇺🇦

merz.bsky.social

30 Oktober 2026 15:38

NIH postdocs win!